National Journal of Biological Sciences https://ojs.wumardan.edu.pk/index.php/njbs Women University Mardan en-US National Journal of Biological Sciences 2790-7805 Distinguishing Iron Deficiency Anemia from Anemia of Chronic Disease Using Hematological Measures https://ojs.wumardan.edu.pk/index.php/njbs/article/view/60 <p>Anemia is a serious public health concern in<br>today’s world which is particularly affecting<br>young children, pregnant women,<br>menstruating adolescent girls and women.<br>The two most common causes of anemia are<br>iron deficiency anemia (IDA) and anemia of<br>chronic disease (ACD), often known as<br>anemia of inflammation. This study aim was<br>to assess the levels of certain hematological<br>parameters, including Hemoglobin<br>Estimation, Mean Corpuscular Volume<br>(MCV), Serum Ferritin, Serum TIBC,<br>Erythrocyte Sedimentation Rate and C -<br>reactive protein to clearly differentiate<br>between iron deficiency anemia and anemia<br>of chronic disease. The study was conducted<br>in Department of Medical Lab Technology,<br>Riphah International University, Islamabad<br>from September 01, 2023 to January 01,<br>2024. A total of 109 samples with 59 of iron<br>deficiency anemia patients and 50 patients of<br>Anemia of chronic disease were assessed for<br>differentiation be these two diseases. The<br>significant level was selected with p-value<br>less than 0.05. Hemoglobin estimation,<br>TIBC, and ESR were significant in our<br>investigation as their p-values were less than<br>0.05. Hence, it concluded that Hemoglobin<br>estimation, total Iron Binding Capacity and<br>Erythrocyte Sedimentation Rate were<br>Hematological parameters that distinguished<br>between Iron Deficiency Anemia and<br>Anemia of Chronic Disease.</p> Wahid Ullah Copyright (c) 2024 National Journal of Biological Sciences 2023-12-31 2023-12-31 4 2 01 09 AN OUTBREAK OF CUTANEOUS LEISHMANIASIS IN THE LOCAL POPULATION OF DIR UPPER, PAKISTAN https://ojs.wumardan.edu.pk/index.php/njbs/article/view/64 <p>Leishmaniasis is an infectious disease caused<br>by intracellular parasitic protozoans<br>belonging to a genus of flagellate protozoa<br>called Leishmania. More than 25 species of<br>the genus Leishmania are present worldwide<br>in which several species are pathogenic to<br>humans. In many cases, cutaneous infection<br>is formed but some species cause<br>subcutaneous or deeper tissues and visceral<br>infection. Cutaneous leishmaniasis is a skin<br>disease caused by Leishmania topica. This<br>disease is transmitted by sandflies. The<br>disease is endemic along the entire Western<br>border of Pakistan. During the present<br>research, the samples were collected from<br>infected people in different areas of Dir<br>Upper. A total of 548 samples were<br>collected among which 346 (63%) were<br>positive cases. In the infected people, 297<br>(86%) were from the local population and 59<br>(14%) from Afghan refugees. A total of 235<br>(68%) males and 111(32%) females were<br>affected. The high prevalence rate (48.5%)<br>was noticed in the age of 11-20 years old<br>people. The prevalence rate between the age<br>of 0-10 was 29.1%. The low prevalence rate<br>(13.6%) was noticed in the people over 30<br>years. Mostly one lesion was noticed in<br>affected people (69%). The patients with<br>two lesions were 22%. The numbers of<br>affected persons with more than two active<br>lesions were little in number i. e. 8.3%. Most<br>of the lesions were reported on the face<br>(36.1%). The second affected part of the<br>body noticed in the study was hand (26.5%).<br>Most of the lesions were dry (81%). It is<br>concluded that a high prevalence rate was<br>observed. People’s awareness is very<br>necessary.</p> Naseer Ullah Copyright (c) 2023 National Journal of Biological Sciences 2023-12-31 2023-12-31 4 2 37 46 SUNFLOWER GROWTH AND YIELD IN RESPONSE TO COMBINED APPLICATION OF FARMYARD MANURE AND INORGANIC FERTILIZERS (NITROGEN AND PHOSPHORUS) https://ojs.wumardan.edu.pk/index.php/njbs/article/view/61 <p>The research was conducted in 2022 in the<br>Agronomy Student's Experiment Farm at<br>Sindh Agriculture University Tando Jam. It<br>used a complete block design with<br>randomization. The main goal was to<br>evaluate how much adding different amounts<br>of FYM and nitrogen-phosphorus affected<br>the growth and seed production ability of<br>sunflowers. The research had five different<br>FYM options and nitrogen-phosphorus<br>levels. The HO-1 variety was given these<br>treatments. The assigned treatments were as<br>follows: T1 = control (no FYM, 0 kg/ha<br>nitrogen and 0 kg/ha phosphorus); T2 =<br>adding a small amount of farmyard manure<br>plus some extra nutrients in the form of<br>nitrogen at a rate of 30kg per hectare, along<br>with an additional quantity of 15 kg per<br>hectare. The best results were seen in T5 (5<br>tons of farm FYM + fertilizers, with 120 kg<br>per hectare of nitrogen and 50 kg per hectare<br>of phosphorus). This method resulted in the<br>most plants on a square meter (9.11), the<br>tallest plant growth at about 248.8 cm high;<br>T5 was closely followed with good results (a<br>lot of FYM plus 120 kg per hectare nitrogen<br>and 50 kg phosphorus). The research<br>indicates that the optimal combination for<br>enhancing sunflower growth and yield<br>includes applying 120 kg ha-1 of nitrogen, 50<br>kg ha-1 of phosphorus, and incorporating 5<br>tons of FYM</p> Asif Ali Kaleri Copyright (c) 2024 National Journal of Biological Sciences 2024-04-25 2024-04-25 4 2 10 17 SEAWEED SELECTION: EXPLORING BEST TYPE FOR BIOPLASTIC PRODUCTION https://ojs.wumardan.edu.pk/index.php/njbs/article/view/63 <p>Extensive research has been conducted on<br>biodegradable materials due to the growing<br>worldwide concern about plastic pollution<br>and the hunt for sustainable alternatives.<br>Because of their environmentally beneficial<br>qualities, bioplastics made from seaweed<br>have become one of these alternatives' most<br>promising solutions. The unique<br>characteristics of seaweed-derived alginate<br>aid in the creation of biodegradable polymers<br>with prospective uses in a range of sectors.<br>The article looks at several types of<br>bioplastics, such as those made of cellulose,<br>polylactic acid, starch, and<br>polyhydroxyalkanoates. Even though these<br>bioplastics have made significant progress,<br>alginate-based bioplastics highlight their<br>enormous potential as a substitute for<br>conventional plastics. Their adaptable<br>qualities—such as excellent biodegradability,<br>tunable mechanical strength, flexibility,<br>environmental friendliness, and<br>renewability—make them ideal for a variety<br>of uses, including 3D printing, packaging,<br>and agricultural applications. The<br>performance and scalability of alginate-based<br>bioplastics might be further improved by the<br>current research and development in this<br>area.</p> Tanveer Majeed Copyright (c) 2024 National Journal of Biological Sciences 2023-12-31 2023-12-31 4 2 18 36